Sulfamethoxazole - Trimethoprim WHAT IS COTRIM P.P.M Oral suspension? COTRIM P.P.M Oral suspension is used for treatment of infections caused by sensitive micro-organisms: genitourinary tract infections, upper and lower respiratory tract infections, otitis, sinusitis, gastrointestinal tract infections, typhoid fever,
Sulfamethoxazole - Trimethoprim
WHAT IS COTRIM P.P.M Oral suspension?
COTRIM P.P.M Oral suspension is used for treatment of infections caused by sensitive micro-organisms: genitourinary tract infections, upper and lower respiratory tract infections, otitis, sinusitis, gastrointestinal tract infections, typhoid fever, Pneumocystis carinii pneumonia.
COMPOSITION:
COTRIM P.P.M Oral suspension:
Sulfamethoxazole …………………. 200mg
Trimethoprim ………………………… 40mg
Excipients: q.s.f ………………………. 5ml
HOW TO USE:
In all cases, you must strictly comply with your doctor’s prescription.
SHAKE WELL BEFORE USE
Dosage:
The usual dose is sulfamethoxazole 15 mg/kg and trimethoprim 3 mg/kg, twice per day, or:
From 6 weeks to 5 months: 2.5 ml, twice per day.
From 6 months to 5 years: 5 ml, twice per day.
From 6 years to 12 years: 10 ml, twice per day.
In severe infections, the dose should be increased by 50%.
Mode of administration: Oral route.
Special cases: acute uncomplicated cystitis / Pneumocystis carinii pneumonitis / renal impairment: the dosage is as directed by your doctor’s prescription.
STORAGE: Store below 30ºC. Protect from light, heat and humidity.
ADVERSE EFFECTS AND WARNING:
The most common observed: gastrointestinal disturbances (nausea, vomiting) and skin reactions (skin rash, urticaria).
Breast-feeding is not recommended in case a mother was being treated with a drug containing sufamethoxazole and trimethoprim.
Metabolic pathways of sulfamethoxazole.
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