Diagnostics, Free Full-Text
Tools based on deep learning models have been created in recent years to aid radiologists in the diagnosis of breast cancer from mammograms. However, the datasets used to train these models may suffer from class imbalance, i.e., there are often fewer malignant samples than benign or healthy cases, which can bias the model towards the healthy class. In this study, we systematically evaluate several popular techniques to deal with this class imbalance, namely, class weighting, over-sampling, and under-sampling, as well as a synthetic lesion generation approach to increase the number of malignant samples. These techniques are applied when training on three diverse Full-Field Digital Mammography datasets, and tested on in-distribution and out-of-distribution samples. The experiments show that a greater imbalance is associated with a greater bias towards the majority class, which can be counteracted by any of the standard class imbalance techniques. On the other hand, these methods provide no benefit to model performance with respect to Area Under the Curve of the Recall Operating Characteristic (AUC-ROC), and indeed under-sampling leads to a reduction of 0.066 in AUC in the case of a 19:1 benign to malignant imbalance. Our synthetic lesion methodology leads to better performance in most cases, with increases of up to 0.07 in AUC on out-of-distribution test sets over the next best experiment.
Diagnostics, Free Full-Text, borderline personality disorder
The Journal of Molecular Diagnostics - Transferring a Quantitative Molecular Diagnostic Test to Multiple Real-Time Quantitative PCR Platforms. Full text is free to all readers as part of the #OpenAccess program
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Diagnostics, Free Full-Text, borderline personality disorder
Diagnostics, Free Full-Text
Diagnostics, Free Full-Text
HWiNFO - Free System Information, Monitoring and Diagnostics
Medtronic deploys remote-controlled ventilators to lessen
Diagnostics, Free Full-Text
Diagnostics, Free Full-Text
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