CleanPlex Limb-Girdle Muscular Dystrophy NGS Panel • NUCLEUS BIOTECH

NUCLEUS BIOTECH • CleanPlex Limb-Girdle Muscular Dystrophy NGS Panel
The CleanPlex® Limb-Girdle Muscular Dystrophy NGS Panel for Illumina® or Ion Torrent™ is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 38 genes associated with Limb-Girdle Muscular Dystrophy. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads. This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries. You have the option to modify the existing content of this pre-designed panel. Please contact us for a quote.

Frontiers Nuclear mechanosignaling in striated muscle diseases

Limb Girdle Muscular Dystrophy Variant Curation Expert Panel - ClinGen

Cells, Free Full-Text

Findings of limb-girdle muscular dystrophy R7 telethonin-related patients from a Chinese neuromuscular center

JCI Insight - Base editing repairs an SGCA mutation in human primary muscle stem cells

Limb-girdle muscular dystrophies — international collaborations for translational research

Genetic characterization of Limb Girdle Muscular Dystrophies and Pompe Disease in a large Argentine cohort - ScienceDirect

Limb Girdle Muscular Dystrophy Variant Curation Expert Panel - ClinGen

Limb-Girdle Muscular Dystrophies

Autosomal Recessive Limb-Girdle Muscular Dystrophies