PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

PDF) Clearance Prediction Methodology Needs Fundamental

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Improving Prediction of Metabolic Clearance Using Quantitative Extrapolation of Results Obtained From Human Hepatic Micropatterned Cocultures Model and by Considering the Impact of Albumin Binding - Journal of Pharmaceutical Sciences

Incorporating Measures of Variability and Uncertainty into the

Incorporating Measures of Variability and Uncertainty into the Prediction of in Vivo Hepatic Clearance from in Vitro Data

In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance

In Vitro - in Vivo Extrapolation of Hepatic Clearance in

In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance

Use of Hepatocytes to Assess the Contribution of Hepatic Uptake to Clearance in Vivo

Quantitative Prediction of Human Hepatic Clearance for P450 and