PDF] Clinicopathologic Characteristics and Causes of

Atrophic endometrium was the most common cause of PMB in both groups, and approximately 12% of cases were associated with gynecological malignancy in older patients. Background This study aimed to reveal the clinicopathologic features and causes of bleeding in older patients with postmenopausal bleeding (PMB) and to investigate the correlation between the ultrasonographic findings and etiology of PMB. Methods We retrospectively analyzed the causes and clinical characteristics of PMB in 498 patients who were diagnosed between January 2007 and December 2017. The population with PMB was divided into 2 groups according to age: Group A (n=204) included individuals more than 65 years of age and group B (n=294) included those less than 65 years of age. Clinical characteristics such as age, parity, underlying conditions, previous surgical history, and previous menopausal hormone therapy were compared between the groups. Cervical cytology testing and transvaginal ultrasonography were performed in all patients with PMB. Endometrial biopsy was performed in all cases of endometrial thickness ≥5 mm. Results We examined 498 patients with PMB. In group A, atrophic endometrium (n=125, 61.27%) was the most common cause of PMB. Twenty-three patients had gynecological malignancy (cervical cancer: n=12, 5.88%; endometrial cancer: n=8, 3.42%; ovarian cancer: n=3, 1.46%), and 30 patients had benign gynecological disease (endometrial polyp: n=10, 4.90%; submucosal myoma: n=6, 2.94%; uterine prolapse: n=7, 3.42%; cervical dysplasia; n=5, 2.45%; cervical polyp: n=2, 0.98%). Forty patients had endometrial thickness ≥5 mm. Eight patients were diagnosed with endometrial cancer. All cases of endometrial cancer were diagnosed with endometrial thickness >10 mm. Conclusion Atrophic endometrium was the most common cause of PMB in both groups, and approximately 12% of cases were associated with gynecological malignancy in older patients.

Clinicopathologic Features of Antibrush Border Antibody Disease - ScienceDirect

PDF) Clinicopathological Study of Eosinophilic Cholecystitis: Five Year Single Institution Experience

Added value of DCER-features to clinicopathologic model for predicting metachronous metastases in rectal cancer patients

PDF) Surgical pathology of colorectal cancer in filipinos: implications for clinical practice1

PDF) Clinicopathologic Characteristics and Causes of Postmenopausal Bleeding in Older Patients

Development and validation of a point-based scoring system for predicting axillary lymph node metastasis and disease outcome in breast cancer using clinicopathological and multiparametric MRI features, Cancer Imaging

Cancers, Free Full-Text

Clinicopathological characteristics and treatment outcomes of oesophageal cancer patients in Uganda - ecancer

IJMS, Free Full-Text

Clinicopathological characteristics and outcomes of lupus nephritis patients with scanty immune depositions in kidney biopsies

PDF) Clinicopathologic Characteristics and Causes of Postmenopausal Bleeding in Older Patients