The synthesis of fluorescent azaheterocycles continues to arouse strong interest due to their great potential for application as sensors and biosensors, luminophores on in the construction of Organic Light-Emitting Diode (OLED) devices, laser and other semiconductor devices, as well as to their potential biological properties as antimicrobial, antifungal, anticancer, antituberculosis antioxidant and anti-HIV agents. The advantages of the azaheterocyclic fluorophores, such as small size, enriched photostability, a wide and tunable spectral range, and, frequently, high brightness, are the reason why these fluorophores are preferred and used in various medical application. Probe structure can be modified to adjust excitation and emission wavelengths, target-binding affinity, chemical reactivity, and subcellular localization.
Frontiers Chemical insights into the synthetic chemistry of five-membered saturated heterocycles—a transition metal–catalyzed approach
PDF) A Review on the Synthesis of Fluorescent Five- and Six-Membered Ring Azaheterocycles
Results of the in vitro growth inhibition (GI%) caused by
λmax (nm) of absorption spectra and λmax (nm) of emission spectra
Enzymatic catalysis favours eight-membered over five-membered ring closure in bicyclomycin biosynthesis
Boron-Containing Helicenes - ChemistryViews
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Costel Moldoveanu's research works
Fluorescent protein chromophores modified with aromatic heterocycles for photodynamic therapy and two-photon fluorescence imaging - Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/D3OB01966G
PDF) Ultrasound-Assisted Synthesis of Fluorescent Azatetracyclic
A) Confocal images of HeLa cells constrained with MTR and o-TPBQ