Chronic diseases with comorbidities or associated risk factors may impair the function of regenerative cells and the regenerative microenvironment. Following this consideration, the vasculogenic conditioning culture (VCC) method was developed to boost the regenerative microenvironment to achieve regeneration-associated cells (RACs), which contain vasculogenic endothelial progenitor cells (EPCs) and anti-inflammatory/anti-immunity cells. Preclinical and clinical studies demonstrate that RAC transplantation is a safe and convenient cell population for promoting ischemic tissue recovery based on its strong vasculogenicity and functionality. The outputs of the scientific reports reviewed in the present study shed light on the fact that RAC transplantation is efficient in curing various diseases. Here, we compactly highlight the universal features of RACs and the latest progress in their translation toward clinics.
IJMS, Free Full-Text
Top) The timeline of the most significant discovery of stem cells
Frontiers The Therapeutic Potential of Mesenchymal Stromal Cells
Extracellular vesicles: Emerging tools as therapeutic agent
Mehdi Hassanpour on LinkedIn: I'm so pleased to share that I'm
Lancet Commission: Stem cells and regenerative medicine - The Lancet
JCM, Free Full-Text
Stem cells: past, present, and future, Stem Cell Research & Therapy
Promises of stem cells in regenerative medicine: the six classes
Stem-cell therapy for cardiac disease
Biology, Free Full-Text
Therapeutic Potential of Skin Stem Cells and Cells of Skin Origin
Regenerative Medicine Market Size & Share Report, 2030