Yunlong Richard Cao on X: It's critical to test how these RBD hotspots could combine to achieve max immune evasion without losing affinity to ACE2. After careful consideration, besides the emerging K478R/F456L

Yunlong Richard Cao on X: Updates on BA.2.86. 1) BA.2.86's ACE2 binding affinity is very high. 2) BA.2.86 has lower fusogenicity than XBB.1.5. 3) BA.2.86's infectivity in Vero cells is similar to

Frontiers The XBB.1.5 slightly increase the binding affinity for host receptor ACE2 and exhibit strongest immune escaping features: molecular modeling and free energy calculation

Passive Immunotherapy Against SARS-CoV-2: From Plasma-Based Therapy to Single Potent Antibodies in the Race to Stay Ahead of the Variants

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

Yunlong Cao Lab Peking University

Yunlong Cao Lab Peking University

Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines

Immune evasion and ACE2 binding affinity contribute to SARS-CoV-2 evolution

Yunlong Richard Cao (@yunlong_cao) / X