5 Pre-mRNA is transcribed from a gene. It is then processed through a
Download scientific diagram | 5 Pre-mRNA is transcribed from a gene. It is then processed through a carefully choreographed set of steps to the mature mRNA which is exported to the cytoplasm. These steps include 5' and 3' modifications, (5' cap: 3' poly A) splicing and specific transport activities. Numerous mechanisms of action for antisense drugs have been identified and they affect many steps post transcription and/or enhance cellular degradation of the RNA (Source: Kurreck, 2003). from publication: Gupta SM & Tomar NR (2012) “Antisense Technology”. In: Biotechnology in medicine and agriculture: principles and practices. (eds. Kumar A, Pareek A & Gupta SM) I. K. International publishing house Pvt. Ltd., New Delhi, India, pp. 297-315. | Antisense Technology 297 Antisense RNA and DNA techniques have been developed as a relatively recent approach to the specific modulation of gene expression in vitro and in vivo. The purpose of this chapter is to lay the foundation of basic concepts and practical uses of | New Delhi, Publishing and Housing | ResearchGate, the professional network for scientists.
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