We provide evidence that in the regenerating basilar papilla, the expression of immune-related genes is tightly controlled, such that four days after damage, they are no longer expressed in newly regenerated hair cells. This is important because the JAK/STAT signaling pathway is highly potent, leadi
Hearing Health Foundation (HHF) is the largest non-profit funder of hearing research. Since 1958, HHF has given away millions of dollars to hearing and balance research, including work that led to cochlear implant technology and now through the Hearing Restoration Project is working on a cure for hearing loss and tinnitus. HHF also publishes Hearing Health magazine, a free consumer resource on hearing loss and related technology, research, and products.
PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing
From mice to men: Will we soon be able to restore hearing loss?
Genetic and Epigenetic Strategies for Promoting Hair Cell Regeneration in the Mature Mammalian Inner Ear
An Essential Signaling Cascade for Hair Cell Regeneration in Birds — Hearing Health Foundation
Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals
Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear
In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice - ScienceDirect
Gone today, hear tomorrow
IJMS, Free Full-Text
Cell-type identity of the avian cochlea - ScienceDirect
Frontiers Recent Advancements in the Regeneration of Auditory Hair Cells and Hearing Restoration
Molecules, Free Full-Text
High-resolution single cell transcriptome analysis of zebrafish sensory hair cell regeneration
Impact 2021 — Hearing Health Foundation
The Latest Research on Hair Cell Regeneration to Restore Hearing — Hearing Health Foundation