Next generation sequencing has lower sequence coverage and poorer
PDF) Li Y, Sidore C, Kang HM, Boehmke M, Abecasis GR.. Low-coverage sequencing: implications for design of complex trait association studies. Genome Res 21: 940-951
Systematic dissection of biases in whole-exome and whole-genome
Low coverage whole genome sequencing enables accurate assessment
SNP discovery (%) by MAF, sequencing depth, and sequencing sample size.
RRResearch: Does variation in sequencing coverage help explain
Efficient phasing and imputation of low-coverage sequencing data
What is a good sequencing depth for bulk RNA-Seq?
Low-Coverage Whole Genome Sequencing - NCI